Life Science Research Professional 1🔍School of Medicine, Stanford, California, United States📁Research📅May 03, 2024 Post Date📅103128 Requisition #The Blood & Marrow Transplantation & Cellular Therapy (BMT-CT) program at Stanford performs autologous and allogeneic transplantations for over 300 patients each year. The program has been very successful with a history of limited morbidity rates and acute mortality that is well below most published reports. In addition to a successful clinical practice, our program researchers are translating their discoveries into new therapies, advancing the efficacy of hematopoietic cell transplantation for patients worldwide.Stanford University is seeking a Life Science Research Professional 1 (LSRP 1) to perform cutting edge, interdisciplinary research in type 1 diabetes (T1D) and transplantation Immunology under direct supervision of the Research Technical Manager (RTM) and Principal Investigator (PI). The incumbent will perform experiments in defined research projects in T1D and transplantation immunology and will be assigned a portion of the research project(s) to handle independently. The LSRP 1 will be expected to make original scientific contributions. Research projects include: 1) immunofluorescent staining of immune cell subsets from humans with or at-risk for T1D, and analysis of those subsets by flow cytometry, 2) sorting of immune cell subsets by FACS, 3) analysis of immune subset function in vitro and 4) perform mass spec studies in support of diabetes, bone marrow and organ/tissue transplantation studies, 5) process development and purification of beta cell antigenic proteins in support of diabetes, bone marrow and organ/tissue transplantation studies 6) consent patients/subjects with or at-risk for T1D for our research studies. Research involves both the performance of immune cell functional assays and the development of others that assess cytokine production, and ability of B, T and myeloid cells to prevent alloimmune rejection of organ/tissue transplants and abrogate autoimmunity. The incumbent is expected to interpret/analyze results, assist in the cleaning/maintenance of the lab, biobanking, inventory of lab reagents/supplies, preparation of buffers/reagents, assist in the maintenance of the mouse colony, preparation of IRB protocols, develop new methods of purifying beta cell antigen proteins, and assist in compliance with EH&S regulations. Other duties may also be assigned. The incumbent will report directly to the Research Technical Manager and Principal Investigator.Duties include:
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