Senior Scientist, Analytical Method Development
Insmed Incorporated

Job Info

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Company Description

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Recognitions

Named Science's Top Employer in 2021, 2022, and 2023

Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we were named the No. 1 company to work for in the biopharma industry in Science's Top Employers Survey for two years in a row.

A Certified Great Place to Work

We believe our company is truly special, and our employees agree. In July 2023, we became Great Place to Work-certified in the U.S. for the third year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, and Best Workplaces for Millennials™ lists.

Overview

Applicants should possess expert skills in analytical chemistry and method development. They will collaborate closely with a multidisciplinary team of scientists focused on the discovery and development of novel drug candidates. More specifically, the candidate will be responsible for, and oversee, activities related to development, optimization, and qualification of analytical methods in support of both small molecule and biologics research and development projects. The ideal candidate will possess a deep understanding of the pharmaceutical development process from pre-clinical development through life-cycle management and be willing to engage with cross-functional teams seeking to develop methods in support of Insmed's platform of new chemical entities.

Responsibilities

Responsibilities:

• Acts as an analytical SME for internal product development using analytical techniques including but not limited to chromatography (HPLC, UPLC, FPLC, SEC, GC, etc.), mass spectroscopy (LC-MS, GC-MS, etc.), and other common analytical techniques in support of preclinical stage small molecule research projects.
• Lead activities related to analytical testing and method qualification, including preparation and review of protocols, SOPs, technical reports, and memo's.
• Develop and implement methods/strategies for quantitation, characterization, and stability testing of drug substances and drug products
• Review literature to learn new methodologies and attend/present at scientific conferences
• Able to evaluate, design and perform method development and qualification employing phase-appropriate approaches at different stages of development.
• Provide scientific guidance and leadership on methods development, optimization, qualification, technical transfer, product comparability, and stability programs related to Insmed's small molecule pipeline
• Mentor and coach scientists for method development and qualification and laboratory instrument troubleshooting
• Interpret complex data and solve scientifically challenging problems by providing direction to the Research Department.
• Maintain accurate, detailed, and timely records of method development and analytical data
• Perform data review to ensure accuracy, completeness, and validity
• Interact with internal partners, CROs and contract laboratories during the development of analytical methods, stability testing, and preparation of technical transfer documents.
• Cross-functional liaison working closely with internal stakeholders, including communication of potential issues/obstacles
• Present scientific results to the research group

Qualifications:

• PhD with 3+ years of experience in the pharmaceutical industry or MS with equivalent qualification and experience combination is required.
• Hands on experience using and interpreting data from various analytical techniques including but not limited to chromatography (HPLC, UPLC, FPLD, SEC, GC, etc.), mass spectroscopy (LC-MS, GC-MS, etc.); experience with Waters/Empower is preferred.
• Experience writing technical documents including but not limited to SOPs, Technical or development reports, and Method qualification reports.
• Ability to define problems, collect data, and draw valid conclusions.
• Capability to establish and maintain cooperative working relationships with internal and external partners.
• Ability to take initiative and work independently while effectively managing timelines.
• Excellent presentation skills both verbal and written.
• Highly proficient in Microsoft Office (Word, Excel, PowerPoint, Outlook).
• Must successfully exhibit Insmed's five (5) core values of Collaboration, Accountability, Passion, Respect and Integrity along with any other position specific competencies.

Travel Requirements

Less than 5% travel

Salary Range

Insmed takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees.

The base salary range for this job is from $115,000.00 to $161,867.00 per year

Compensation & Benefits

We're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including:

• Flexible approach to where and how we work, regionally based
• Competitive compensation package including bonus
• Stock options and RSU awards
• Employee Stock Purchase Plan (ESPP)
• Flexible Vacation Policy
• Generous paid holiday schedule and winter break

ADDITIONAL U.S. BENEFITS:

• 401(k) plan with company match
• Medical, dental, and vision plans
• Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance
• Company-provided short and long-term disability benefits
• Unique offerings of pet, legal, and supplemental life insurance
• Flexible spending accounts for medical and dependent care
• Accident and Hospital Indemnity insurance
• Employee Assistance Program (EAP)
• Mental Health on-line digital resource
• Well-being reimbursement
• Paid leave benefits for new parents
• Paid time off to volunteer
• On-site, no-cost fitness center at our U.S. headquarters

Additional Information

Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

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